Rationale for the efficiency of transcranial magnetic stimulation in multiple sclerosis

The aim. Based on the analysis and comprehensive clinical neurological evaluation of results to substantiate effectiveness transcranial magnetic stimulation (TMS) in treatment rehabilitation patients with multiple sclerosis (MS).
 Methods. A total 110 MS were included study. control group consisted 30 who received pathogenetic therapy 80 underwent a course rhythmic (rTMS) together therapy.
 Results. obtained during study indicate complex multifactorial nature fatigue its significant impact manifestations MS. Also, use rTMS reduced severity main symptoms improvement overall EDSS scale receiving was statistically significant: from 5.0±1.9 points 4.5±2.0 (p<0.01), comparison (p>0.05). Under influence TMS, gait function improved, but these indicators insignificant greatest effect also extended cognitive psychosocial components. patterns are confirmed SCA FS scales. Involvement allowed achieve reduction all components fatigue: 76.0±20.9 75.5±20.5 (p<0.05).
 data confirm effectiveness, safety viability non-invasive neuromodulation by MS.
 Conclusions. has positive fatigue, both motor cognitive, at types different stages progression. Non-invasiveness, ease use, possibility differentiated allow clinic become an important component active drug non-drug